Carbapenem-resistant biofilm-producing multidrug resistant Klebsiella pneumoniae induced hospital-acquired infections and analysis of resistant genes

Palanisamy Manikandan

doi:10.5455/mjhs.2023.01.013

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Majmaah J Heal Sci. 2023; 11(1): 161-178

doi: 10.5455/mjhs.2023.01.013

Carbapenem-resistant biofilm-producing multidrug resistant Klebsiella pneumoniae induced hospital-acquired infections and analysis of resistant genes

Palanisamy Manikandan.

Abstract
In recent years, drug resistance has caused a significant number of fatalities. This review focuses on the emergence of medication resistance in Klebsiella pneumoniae strains associated with biofilm development, neonatal sepsis, aging, and secondary K. pneumoniae infection in COVID-19 cases. This review is an exclusive survey of >200 research articles and >100 review articles indexed in the Web of Science list with the keywords “K. pneumoniae,” “drug resistance,” “sepsis,” “neonatal sepsis,” “sepsis in older age,” “secondary infection,” “biofilm production,” “secondary infection in COVID-19,” “drug resistance genes,” and “whole genome sequencing”. In order to protect antibiotic susceptibility and to provide an overview of the biofilm forming mechanisms among gram-negative bacteria, the review discusses the function of multidrug-resistant K. pneumoniae in the production of biofilms. Additionally, K. pneumoniae’s role in contemporary cases of sepsis, spread of medication resistance in hospitals, and sepsis caused by K. pneumoniae in the geriatric age group are discussed. A summary of current approaches and the identification of drug resistance genes utilizing a whole genome sequencing technique are also reviewed in this article.

Key words: Klebsiella pneumoniae, Biofilm, Drug resistance, Carbapenemresistance, Plasmid, Gene

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Pubmed Style

Palanisamy Manikandan. Carbapenem-resistant biofilm-producing multidrug resistant Klebsiella pneumoniae induced hospital-acquired infections and analysis of resistant genes. Majmaah J Heal Sci. 2023; 11(1): 161-178. doi:10.5455/mjhs.2023.01.013

Web Style

Palanisamy Manikandan. Carbapenem-resistant biofilm-producing multidrug resistant Klebsiella pneumoniae induced hospital-acquired infections and analysis of resistant genes. https://www.mjhs-mu.org/?mno=114555 [Access: September 13, 2024]. doi:10.5455/mjhs.2023.01.013

AMA (American Medical Association) Style

Palanisamy Manikandan. Carbapenem-resistant biofilm-producing multidrug resistant Klebsiella pneumoniae induced hospital-acquired infections and analysis of resistant genes. Majmaah J Heal Sci. 2023; 11(1): 161-178. doi:10.5455/mjhs.2023.01.013

Vancouver/ICMJE Style

Palanisamy Manikandan. Carbapenem-resistant biofilm-producing multidrug resistant Klebsiella pneumoniae induced hospital-acquired infections and analysis of resistant genes. Majmaah J Heal Sci. (2023), [cited September 13, 2024]; 11(1): 161-178. doi:10.5455/mjhs.2023.01.013

Harvard Style

Palanisamy Manikandan (2023) Carbapenem-resistant biofilm-producing multidrug resistant Klebsiella pneumoniae induced hospital-acquired infections and analysis of resistant genes. Majmaah J Heal Sci, 11 (1), 161-178. doi:10.5455/mjhs.2023.01.013

Turabian Style

Palanisamy Manikandan. 2023. Carbapenem-resistant biofilm-producing multidrug resistant Klebsiella pneumoniae induced hospital-acquired infections and analysis of resistant genes. Majmaah Journal of Health Sciences, 11 (1), 161-178. doi:10.5455/mjhs.2023.01.013

Chicago Style

Palanisamy Manikandan. "Carbapenem-resistant biofilm-producing multidrug resistant Klebsiella pneumoniae induced hospital-acquired infections and analysis of resistant genes." Majmaah Journal of Health Sciences 11 (2023), 161-178. doi:10.5455/mjhs.2023.01.013

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

Palanisamy Manikandan (2023) Carbapenem-resistant biofilm-producing multidrug resistant Klebsiella pneumoniae induced hospital-acquired infections and analysis of resistant genes. Majmaah Journal of Health Sciences, 11 (1), 161-178. doi:10.5455/mjhs.2023.01.013

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