Human trials: Manuscripts reporting data from research conducted on humans must include a statement of assurance in the methods section of the manuscript reading that:

(1)  Informed consent was obtained from each patient included in the study and

(2)  The study protocol conforms to the ethical guidelines of the 1975 declaration of helsinki as reflected in a priori approval by the institution's human research committee.

Animal trials: Manuscripts reporting experiments using animals must include a statement giving assurance that all animals received human care and that study protocols comply with the institution's guidelines. Statistical methods used should be outlined.