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Original Article
Online Published: 17 Mar 2018
 


The Use of Nuclear Medicine Invitro Technology to Study the Effect of Malnutrition on children’s Thyroid Function

Nagi I Ali, Abdullah O Alamoudi, Yousif Mohamed Y Abdullah.

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Abstract
In this study, forty-nine – under five years, male & female Sudanese children, presented with protein energy malnutrition (PEM, Kwash) according to the WHO criteria have been studied for their thyroid function and other biochemical Parameters. Triiodothyronine (T3), Thyroxine (T4) and Thyroid Stimulating Hormone (TSH), as a thyroid function indicators, the study included determination of Thyroglobulin (TG), Ferritin, Protein Moreover, Hemoglobin levels in serum. The study was done in different hospitals in Khartoum state. Patients being assessed & examined by pediatricians using a unified clinical protocol and a questionnaire for patient’s characteristics. Thyroid hormones and Ferritin were measured by a sensitive radioimmunoassay (RIA) Technique in 49 children with malnutrition as well as a control group of 20 healthy children. When the results of malnourished children compared to normal children showed that; 22% of malnourished children have severe hypothyroidism (T4 < 30 mol/l) and (T3 < 0.5 mol/l) as the reference range (50 – 150mol/l) and (0.8 – 3 mol/l) respectively. The mean level of TSH for patients was within the normal range but it was lower than the mean of TSH levels for controls. The mean values of TG and Ferritin for patients was higher than that of controls. Protein and Hemoglobin values showed low levels in Patients and negative clinical correlation between Ferritin and Hemoglobin has been found. Our conclusion of this study states that, malnutrition has severe effects on thyroid function.

Key words: Nuclear Medicine, Thyroid Function


 
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How to Cite this Article
Pubmed Style

Ali NI, Alamoudi AO, Abdullah YMY. The Use of Nuclear Medicine Invitro Technology to Study the Effect of Malnutrition on children’s Thyroid Function. Majmaah J Heal Sci. 2017; 5(2): 15-20. doi:10.5455/mjhs.2017.02.003

Web Style

Ali NI, Alamoudi AO, Abdullah YMY. The Use of Nuclear Medicine Invitro Technology to Study the Effect of Malnutrition on children’s Thyroid Function. https://www.mjhs-mu.org/?mno=294047 [Access: September 12, 2024]. doi:10.5455/mjhs.2017.02.003

AMA (American Medical Association) Style

Ali NI, Alamoudi AO, Abdullah YMY. The Use of Nuclear Medicine Invitro Technology to Study the Effect of Malnutrition on children’s Thyroid Function. Majmaah J Heal Sci. 2017; 5(2): 15-20. doi:10.5455/mjhs.2017.02.003


Vancouver/ICMJE Style

Ali NI, Alamoudi AO, Abdullah YMY. The Use of Nuclear Medicine Invitro Technology to Study the Effect of Malnutrition on children’s Thyroid Function. Majmaah J Heal Sci. (2017), [cited September 12, 2024]; 5(2): 15-20. doi:10.5455/mjhs.2017.02.003


Harvard Style

Ali, N. I., Alamoudi, . A. O. & Abdullah, . Y. M. Y. (2017) The Use of Nuclear Medicine Invitro Technology to Study the Effect of Malnutrition on children’s Thyroid Function. Majmaah J Heal Sci, 5 (2), 15-20. doi:10.5455/mjhs.2017.02.003


Turabian Style

Ali, Nagi I, Abdullah O Alamoudi, and Yousif Mohamed Y Abdullah. 2017. The Use of Nuclear Medicine Invitro Technology to Study the Effect of Malnutrition on children’s Thyroid Function. Majmaah Journal of Health Sciences, 5 (2), 15-20. doi:10.5455/mjhs.2017.02.003


Chicago Style

Ali, Nagi I, Abdullah O Alamoudi, and Yousif Mohamed Y Abdullah. "The Use of Nuclear Medicine Invitro Technology to Study the Effect of Malnutrition on children’s Thyroid Function." Majmaah Journal of Health Sciences 5 (2017), 15-20. doi:10.5455/mjhs.2017.02.003


MLA (The Modern Language Association) Style

Ali, Nagi I, Abdullah O Alamoudi, and Yousif Mohamed Y Abdullah. "The Use of Nuclear Medicine Invitro Technology to Study the Effect of Malnutrition on children’s Thyroid Function." Majmaah Journal of Health Sciences 5.2 (2017), 15-20. Print. doi:10.5455/mjhs.2017.02.003


APA (American Psychological Association) Style

Ali, N. I., Alamoudi, . A. O. & Abdullah, . Y. M. Y. (2017) The Use of Nuclear Medicine Invitro Technology to Study the Effect of Malnutrition on children’s Thyroid Function. Majmaah Journal of Health Sciences, 5 (2), 15-20. doi:10.5455/mjhs.2017.02.003




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