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Case Report 


Primary cutaneous diffuse large B-cell lymphoma NOS with short-term relapse

Salem A. Balhamar, Mohammed S. Alqarni, Abdulrahman N. Alotaibi, Abdulrahman M. Alkathiry, Areej M. Al Nemer, Osamah J. Refai, Ali M. Al-Amri.

Abstract
Primary cutaneous B-cell lymphomas are a unique, heterogeneous group of lymphoproliferative dis¬orders without evidence of extra-cutaneous manifestations. Primary cutaneous diffuse large B-cell lymphomas (PCDLBCLs) are aggressive neoplasms with poor prognosis. The infiltrate in some cases could involve the underlying subcutaneous tissues, but rarely reported. Accurate diagnosis is man¬datory as these patients respond well to systemic anthracycline-based chemotherapy (R-CHOP). In this article, we report a case of PCDLBCL/NOS that presented with skin manifestations and was diagnosed based on clinical features, pathology, and immunohistochemical staining. The patients were treated with systemic chemotherapy, CHOP-R, and responded well and the PET scan showed no evidence of residual disease after the 5th cycle. After 3 months of follow-up, the patient succumbed to his disease involving almost all his skin.

Key words: Lymphoma, DLBCL, Cutaneous, Relapse, Case Report


 
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How to Cite this Article
Pubmed Style

Balhamar SA, Alqarni MS, Alotaibi AN, Alkathiry AM, Nemer AMA, Refai OJ, Al-Amri AM. Primary cutaneous diffuse large B-cell lymphoma NOS with short-term relapse. Majmaah J Heal Sci. 2024; 12(1): 173-177. doi:10.5455/mjhs.2024.01.015

Web Style

Balhamar SA, Alqarni MS, Alotaibi AN, Alkathiry AM, Nemer AMA, Refai OJ, Al-Amri AM. Primary cutaneous diffuse large B-cell lymphoma NOS with short-term relapse. https://www.mjhs-mu.org/?mno=159707 [Access: January 15, 2024]. doi:10.5455/mjhs.2024.01.015

AMA (American Medical Association) Style

Balhamar SA, Alqarni MS, Alotaibi AN, Alkathiry AM, Nemer AMA, Refai OJ, Al-Amri AM. Primary cutaneous diffuse large B-cell lymphoma NOS with short-term relapse. Majmaah J Heal Sci. 2024; 12(1): 173-177. doi:10.5455/mjhs.2024.01.015


Vancouver/ICMJE Style

Balhamar SA, Alqarni MS, Alotaibi AN, Alkathiry AM, Nemer AMA, Refai OJ, Al-Amri AM. Primary cutaneous diffuse large B-cell lymphoma NOS with short-term relapse. Majmaah J Heal Sci. (2024), [cited January 15, 2024]; 12(1): 173-177. doi:10.5455/mjhs.2024.01.015


Harvard Style

Balhamar, S. A., Alqarni, . M. S., Alotaibi, . A. N., Alkathiry, . A. M., Nemer, . A. M. A., Refai, . O. J. & Al-Amri, . A. M. (2024) Primary cutaneous diffuse large B-cell lymphoma NOS with short-term relapse. Majmaah J Heal Sci, 12 (1), 173-177. doi:10.5455/mjhs.2024.01.015


Turabian Style

Balhamar, Salem A., Mohammed S. Alqarni, Abdulrahman N. Alotaibi, Abdulrahman M. Alkathiry, Areej M. Al Nemer, Osamah J. Refai, and Ali M. Al-Amri. 2024. Primary cutaneous diffuse large B-cell lymphoma NOS with short-term relapse. Majmaah Journal of Health Sciences, 12 (1), 173-177. doi:10.5455/mjhs.2024.01.015


Chicago Style

Balhamar, Salem A., Mohammed S. Alqarni, Abdulrahman N. Alotaibi, Abdulrahman M. Alkathiry, Areej M. Al Nemer, Osamah J. Refai, and Ali M. Al-Amri. "Primary cutaneous diffuse large B-cell lymphoma NOS with short-term relapse." Majmaah Journal of Health Sciences 12 (2024), 173-177. doi:10.5455/mjhs.2024.01.015


MLA (The Modern Language Association) Style

Balhamar, Salem A., Mohammed S. Alqarni, Abdulrahman N. Alotaibi, Abdulrahman M. Alkathiry, Areej M. Al Nemer, Osamah J. Refai, and Ali M. Al-Amri. "Primary cutaneous diffuse large B-cell lymphoma NOS with short-term relapse." Majmaah Journal of Health Sciences 12.1 (2024), 173-177. Print. doi:10.5455/mjhs.2024.01.015


APA (American Psychological Association) Style

Balhamar, S. A., Alqarni, . M. S., Alotaibi, . A. N., Alkathiry, . A. M., Nemer, . A. M. A., Refai, . O. J. & Al-Amri, . A. M. (2024) Primary cutaneous diffuse large B-cell lymphoma NOS with short-term relapse. Majmaah Journal of Health Sciences, 12 (1), 173-177. doi:10.5455/mjhs.2024.01.015




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