Prevalence, Predictors and Prognostic Impact of Renal Dysfunction among Hospitalized Patients with Systolic Heart Failure

Raneem Abdulraheem Alraheili; Mohammed Abdullah Saeed; Amjad Taj Karam; Faris Abdulmuti Alhejaili; Faisal Owdah Alatawi; Sami Abdo Al-Dubai

doi:10.5455/mjhs.2021.02.004

Original Article

Majmaah J Heal Sci. 2021; 9(2): 23-35

doi: 10.5455/mjhs.2021.02.004

Prevalence, Predictors and Prognostic Impact of Renal Dysfunction among Hospitalized Patients with Systolic Heart Failure

Raneem Abdulraheem Alraheili, Mohammed Abdullah Saeed, Amjad Taj Karam, Faris Abdulmuti Alhejaili, Faisal Owdah Alatawi, Sami Abdo Al-Dubai.

Abstract
Background and Aim: The interaction between heart and kidneys has increased, and parts of the pathophysiological background for the cardiorenal syndrome have been established. This study aimed to determine the prevalence, predictors, and prognostic impact of Renal Dysfunction (RD) among hospitalized patients with systolic Heart Failure (HF).

Methods: This cross-sectional study included 1559 patients, who were admitted with a diagnosis of systolic HF during the period from 1-March-2011 till 20-June- 2019 at Madinah cardiac center. RD was defined as estimated glomerular filtration rate < 60 mL/min/1.73 m2.

Results: Of the total of 1559 patients, 67.2% were males, 51.3% were hypertensive, 56.1% were diabetic and 49.1% were anemic. 60.9% of patients had RD. HF patients with RD were significantly older (p<0.001), had a history of Hypertension (HTN) (p<0.001), Diabetes Mellitus (DM) (p<0.001), anemia (p<0.001), stroke (p<0.003) and smoking (p<0.001). Multivariate analysis showed that older age (OR, 1.1; 95% CI, 1.05-1.07; p<0.001), history of DM (OR, 1.5; 95% CI, 1.14-1.86; p=0.003), HTN (OR, 1.4; 95% CI,1.11-1.81; p=0.005), and anemia (OR, 1.6; 95% CI,1.30-2.06; p<0.001) were the predictors of RD. Patients with RD had a significantly higher death rate and total length stay (p<0.001). However, the hospitalization rate was not significant (p=0.111).

Conclusions: About 60.9% of systolic HF patients had RD. Older age, history of DM, HTN, and anemia were predictors of RD. Patients with RD had a higher death rate and a total length of stay.

Key words: Renal Dysfunction, Heart Failure, Glomerular Filtration Rate, Cardiorenal Syndrome

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How to Cite this Article

Pubmed Style

Alraheili RA, Saeed MA, Karam AT, Alhejaili FA, Alatawi FO, Al-Dubai SA. Prevalence, Predictors and Prognostic Impact of Renal Dysfunction among Hospitalized Patients with Systolic Heart Failure. Majmaah J Heal Sci. 2021; 9(2): 23-35. doi:10.5455/mjhs.2021.02.004

Web Style

Alraheili RA, Saeed MA, Karam AT, Alhejaili FA, Alatawi FO, Al-Dubai SA. Prevalence, Predictors and Prognostic Impact of Renal Dysfunction among Hospitalized Patients with Systolic Heart Failure. https://www.mjhs-mu.org/?mno=12270 [Access: December 05, 2023]. doi:10.5455/mjhs.2021.02.004

AMA (American Medical Association) Style

Alraheili RA, Saeed MA, Karam AT, Alhejaili FA, Alatawi FO, Al-Dubai SA. Prevalence, Predictors and Prognostic Impact of Renal Dysfunction among Hospitalized Patients with Systolic Heart Failure. Majmaah J Heal Sci. 2021; 9(2): 23-35. doi:10.5455/mjhs.2021.02.004

Vancouver/ICMJE Style

Alraheili RA, Saeed MA, Karam AT, Alhejaili FA, Alatawi FO, Al-Dubai SA. Prevalence, Predictors and Prognostic Impact of Renal Dysfunction among Hospitalized Patients with Systolic Heart Failure. Majmaah J Heal Sci. (2021), [cited December 05, 2023]; 9(2): 23-35. doi:10.5455/mjhs.2021.02.004

Harvard Style

Alraheili, R. A., Saeed, . M. A., Karam, . A. T., Alhejaili, . F. A., Alatawi, . F. O. & Al-Dubai, . S. A. (2021) Prevalence, Predictors and Prognostic Impact of Renal Dysfunction among Hospitalized Patients with Systolic Heart Failure. Majmaah J Heal Sci, 9 (2), 23-35. doi:10.5455/mjhs.2021.02.004

Turabian Style

Alraheili, Raneem Abdulraheem, Mohammed Abdullah Saeed, Amjad Taj Karam, Faris Abdulmuti Alhejaili, Faisal Owdah Alatawi, and Sami Abdo Al-Dubai. 2021. Prevalence, Predictors and Prognostic Impact of Renal Dysfunction among Hospitalized Patients with Systolic Heart Failure. Majmaah Journal of Health Sciences, 9 (2), 23-35. doi:10.5455/mjhs.2021.02.004

Chicago Style

Alraheili, Raneem Abdulraheem, Mohammed Abdullah Saeed, Amjad Taj Karam, Faris Abdulmuti Alhejaili, Faisal Owdah Alatawi, and Sami Abdo Al-Dubai. "Prevalence, Predictors and Prognostic Impact of Renal Dysfunction among Hospitalized Patients with Systolic Heart Failure." Majmaah Journal of Health Sciences 9 (2021), 23-35. doi:10.5455/mjhs.2021.02.004

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

Alraheili, R. A., Saeed, . M. A., Karam, . A. T., Alhejaili, . F. A., Alatawi, . F. O. & Al-Dubai, . S. A. (2021) Prevalence, Predictors and Prognostic Impact of Renal Dysfunction among Hospitalized Patients with Systolic Heart Failure. Majmaah Journal of Health Sciences, 9 (2), 23-35. doi:10.5455/mjhs.2021.02.004

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