ISSN 1658-645X
 

Review Article 


Use of FDG-PET/CT for Biological Target Volume Definition in Head and Neck Cancer

Abdulrahman A Alfuraih.

Abstract
Most of patients with head and neck cancers (HNC) need curative radiotherapy either as radical treatment or in the postoperative adjuvant setting. Accurate target definition is paramount to ensure a good outcome of radiotherapy. Pretreatment Computed Tomography (CT) is regularly performed for radiation therapy planning, which both guides dose calculation and aids accurately contouring the tumor volume. Nevertheless, when using CT, the low resolution of soft- tissue and the dental artifacts may render the primary tumor identification difficult. The interobserver inconsistency on the definition of the radiation target volume is additionally a generally perceived issue. With the increase of the frequency of HNC treatment by Intensity-modulated radiotherapy (IMRT), the accurate target volume delineation performed by using Fluorodeoxy D-glucose positron emission tomography combined to CT (FDG-PET/CT) had become even more significant. Nevertheless, the ideal technique for precisely deciding the exact margins and form of the biologic tumor volume (BTV) remains challenging. FDG-PET/CT can define BTVs either for escalation of dose or alternative treatment strategies. Debatable issues still exist on the role of FDG PET/CT during radiotherapy treatment. Moreover, some new PET tracers, other than FDG, have been investigated for imaging specific biologic tumor characteristics in HNC. The purpose of this narrative review is to discuss the use of FDG-PET/CT for BTV definition before and during delivery of radiotherapy for HNC with attention to PET tracers other than FDG.

Key words: FDG-PET/CT, Biologic target volume, Head and neck cancer, Radiotherapy planning.


 
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Pubmed Style

Abdulrahman A Alfuraih. Use of FDG-PET/CT for Biological Target Volume Definition in Head and Neck Cancer. Majmaah J Heal Sci. 2018; 6(1): 61-82.


Web Style

Abdulrahman A Alfuraih. Use of FDG-PET/CT for Biological Target Volume Definition in Head and Neck Cancer. http://www.mjhs-mu.org/?mno=297306 [Access: May 25, 2018].


AMA (American Medical Association) Style

Abdulrahman A Alfuraih. Use of FDG-PET/CT for Biological Target Volume Definition in Head and Neck Cancer. Majmaah J Heal Sci. 2018; 6(1): 61-82.



Vancouver/ICMJE Style

Abdulrahman A Alfuraih. Use of FDG-PET/CT for Biological Target Volume Definition in Head and Neck Cancer. Majmaah J Heal Sci. (2018), [cited May 25, 2018]; 6(1): 61-82.



Harvard Style

Abdulrahman A Alfuraih (2018) Use of FDG-PET/CT for Biological Target Volume Definition in Head and Neck Cancer. Majmaah J Heal Sci, 6 (1), 61-82.



Turabian Style

Abdulrahman A Alfuraih. 2018. Use of FDG-PET/CT for Biological Target Volume Definition in Head and Neck Cancer. Majmaah Journal of Health Sciences, 6 (1), 61-82.



Chicago Style

Abdulrahman A Alfuraih. "Use of FDG-PET/CT for Biological Target Volume Definition in Head and Neck Cancer." Majmaah Journal of Health Sciences 6 (2018), 61-82.



MLA (The Modern Language Association) Style

Abdulrahman A Alfuraih. "Use of FDG-PET/CT for Biological Target Volume Definition in Head and Neck Cancer." Majmaah Journal of Health Sciences 6.1 (2018), 61-82. Print.



APA (American Psychological Association) Style

Abdulrahman A Alfuraih (2018) Use of FDG-PET/CT for Biological Target Volume Definition in Head and Neck Cancer. Majmaah Journal of Health Sciences, 6 (1), 61-82.





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