Abstract
Background and Aim: Arthritis is an inflammation infects any joint of the body or tissues around that joint. As any disease, arthritis has an effect on health-related quality of life (HRQoL) in adult patients. Although many researches showed how smoking can worse the condition of arthritis as a disease, there is not a specific study investigated the effect of smoking on HRQoL in adult patients of arthritis, which is the goal of this study.

Methods: This study used a publicly open data source from the 2017-Behavioral Risk Factor Surveillance System (BRFSS) in the United States. It is a health survey using the telephone in order to collect data from the United States residents. There were 450,013 participants in this survey. Different descriptive, inferential, and predictive analysis methods were used by the Statistical Analysis System (9.4 version ) to achieve the goal of this study.

Results: There were 450,013 participants in 2017-BRFSS, 147,288 of them were adult patients of arthritis. 63,466 of these participants in BRFSS-2017 were current smokers. 13,542 of these smokers were adults patients of arthritis. This study showed a statistically significant effect of the association between arthritis and smoking on activity limitations, physical health problems, and mental health problems.

Conclusions: Smoking has a great effect on health-related quality of life (HRQOL) in adult patients of arthritis. Smoking increased each of the activity limitations in adult patients of arthritis by 164%, physical health problems by 34.75%, mental health problems by 20.58% in adult patients of arthritis.

Key words: Arthritis; Smoking; HRQoL; BRFSS; SAS Analysis