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Case Report 


Methotrexate-induced Hyponatremia in Rheumatoid Arthritis: A Case Report

Bader A. Almehmadi.


Abstract
Methotrexate is a widely used medication with immunosuppressive and immunomodulatory effects on cancers and autoimmune diseases, it is known that hyponatremia may be a side effect of its use in high doses when treating cancers, but it is unknown in low doses when used as an immunomodulator. Hyponatremia may be asymptomatic initially but can progress to fatal consequences if left untreated. Here we present a case of hyponatremia secondary to a low dose of methotrexate in an elderly patient with rheumatoid arthritis.

Key words: Methotrexate, hyponatremia, rheumatoid arthritis, SIADH, adverse event.


 
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Pubmed Style

Bader A. Almehmadi. Methotrexate-induced Hyponatremia in Rheumatoid Arthritis: A Case Report. Majmaah J Heal Sci. 2023; 11(3): 109-114. doi:10.5455/mjhs.2023.03.012

Web Style

Bader A. Almehmadi. Methotrexate-induced Hyponatremia in Rheumatoid Arthritis: A Case Report. https://www.mjhs-mu.org/?mno=147249 [Access: September 12, 2024]. doi:10.5455/mjhs.2023.03.012

AMA (American Medical Association) Style

Bader A. Almehmadi. Methotrexate-induced Hyponatremia in Rheumatoid Arthritis: A Case Report. Majmaah J Heal Sci. 2023; 11(3): 109-114. doi:10.5455/mjhs.2023.03.012


Vancouver/ICMJE Style

Bader A. Almehmadi. Methotrexate-induced Hyponatremia in Rheumatoid Arthritis: A Case Report. Majmaah J Heal Sci. (2023), [cited September 12, 2024]; 11(3): 109-114. doi:10.5455/mjhs.2023.03.012


Harvard Style

Bader A. Almehmadi (2023) Methotrexate-induced Hyponatremia in Rheumatoid Arthritis: A Case Report. Majmaah J Heal Sci, 11 (3), 109-114. doi:10.5455/mjhs.2023.03.012


Turabian Style

Bader A. Almehmadi. 2023. Methotrexate-induced Hyponatremia in Rheumatoid Arthritis: A Case Report. Majmaah Journal of Health Sciences, 11 (3), 109-114. doi:10.5455/mjhs.2023.03.012


Chicago Style

Bader A. Almehmadi. "Methotrexate-induced Hyponatremia in Rheumatoid Arthritis: A Case Report." Majmaah Journal of Health Sciences 11 (2023), 109-114. doi:10.5455/mjhs.2023.03.012


MLA (The Modern Language Association) Style

Bader A. Almehmadi. "Methotrexate-induced Hyponatremia in Rheumatoid Arthritis: A Case Report." Majmaah Journal of Health Sciences 11.3 (2023), 109-114. Print. doi:10.5455/mjhs.2023.03.012


APA (American Psychological Association) Style

Bader A. Almehmadi (2023) Methotrexate-induced Hyponatremia in Rheumatoid Arthritis: A Case Report. Majmaah Journal of Health Sciences, 11 (3), 109-114. doi:10.5455/mjhs.2023.03.012




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